Genesis 22:10

And Abraham stretched forth his hand, and took the knife to slay his son.


Geneva Bible - And Abraham stretching forth his hand, took the knife to kill his son.

Scofield Bible - Isaac is a protype of Christ (Abraham gave his only son as a sacrifice, based on faith in God).  Isaac, who was ready to go to his death willingly.  Isaac, the seed of promise as the future generations promised by God, just as Jesus is the one through whom all who will be saved must come.  The ram would be the substitute, and Jesus was the substitute for eternity of the annual sacrifice for atonement of sins.